Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
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15.5K Views
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12:36 min
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March 14th, 2020
DOI :
March 14th, 2020
•Michael A. Pearen*1, Hong Kiat Lim*1, Francis D. Gratte2,3, Manuel A. Fernandez-Rojo1,4,5, Sujeevi K. Nawaratna6, Geoffrey N. Gobert7, John K. Olynyk8,9, Janina E. E. Tirnitz-Parker2,10, Grant A. Ramm1,4
1Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, 2School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, 3School of Veterinary and Life Sciences, Murdoch University, 4School of Medicine, The University of Queensland, 5Madrid Institute for Advanced Studies (IMDEA) in Food, CEI UAM+CSIC, 6School of Medicine, Griffith University, 7School of Biological Sciences, Queen's University Belfast, 8Department of Gastroenterology & Hepatology, Fiona Stanley and Fremantle Hospital Group, 9School of Medical and Health Sciences, Edith Cowan University, 10Centre for Cell Therapy and Regenerative Medicine, School of Biomedical Sciences, University of Western Australia
Rozdziały w tym wideo
0:00
Introduction
1:23
Setup of the Vibratome
3:15
Liver Removal and Preparation
6:07
Production of Liver Slices
10:14
Results: Viability, Collagen, and Effects of Selected Bile Acids
11:45
Conclusion
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