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Easy and Accurate Mechano-profiling on Micropost Arrays

DOI :

10.3791/53350-v

November 17th, 2015

November 17th, 2015

10,968 Views

1University of Zurich, Balgrist University Hospital, 2Institute for Biomechanics, ETH Zurich

Described are protocols for quantifying mechanical interactions between adherent cells and microstructured substrates. These interactions are closely linked to essential cell behaviors including migration, proliferation, differentiation, and apoptosis. The protocols present an open-source image analysis software called MechProfiler, which enables determination of involved forces for each micropost.

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Keywords Micropost Arrays

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