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Assessing Biofilm Dispersal in Murine Wounds

DOI :

10.3791/62136-v

August 7th, 2021

August 7th, 2021

3,682 Views

1Department of Surgery, Texas Tech University Health Sciences Center, 2Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, 3TTUHSC Surgery Burn Center of Research Excellence, Texas Tech University Health Sciences Center

Here, we describe ex vivo and in vivo methods for assessing bacterial dispersal from a wound infection in mice. This protocol can be utilized to test the efficacy of topical antimicrobial and anti-biofilm therapies, or to assess the dispersal capacity of different bacterial strains or species.

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