Roux-en-Y gastric bypass is a commonly performed procedure for the treatment of severe obesity and type 2 diabetes. However, the exact mechanisms contributing to weight loss and metabolic improvement are not well understood and multiple factors ar
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Roux-en-Y gastric bypass (RYGB) is performed to treat obesity and diabetes. However, the mechanisms underlying RYGB's efficacy are not fully understood, and studies are limited by technical difficulty leading to high mortality in animal models. This article provides instructions on how to perform RYGB in rats with high success rates.