Results: DNA Damage Response in Human iPS Cells and iPS-derived Cardiomyocytes
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Conclusion
Transcript
For neonatal diseases such as cardiomyopathy, regenerative therapy using induced pluripotent stem cell-derived cells has massive potential. However, in vitro accelerated cell growth leads to DNA damage by accumulated metabolites such as reactive o
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Here, we provide a detailed description of an experimental setup for an analysis of the assessment of DNA integrity in stem cells prior to cell transplantation.