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Chronic Salmonella Infection Induced Intestinal Fibrosis

DOI :

10.3791/60068-v

September 22nd, 2019

September 22nd, 2019

6,521 Views

1The Biomedical Research Centre, University of British Columbia

This protocol describes a mouse model of Salmonella driven intestinal fibrosis that resembles key pathological hallmarks of Crohn’s disease including transmural inflammation and fibrosis. This method can be used to evaluate host factors that alter fibrotic outcomes using mutant mice maintained on a C57Bl/6 genetic background.

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Chronic Salmonella Infection

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