JoVE Logo
Faculty Resource Center

Sign In

Microcrystal Electron Diffraction of Small Molecules

DOI :

10.3791/62313-v

March 15th, 2021

March 15th, 2021

4,652 Views

1Howard Hughes Medical Institute, University of California Los Angeles, 2Department of Biological Chemistry, University of California Los Angeles, 3Department of Physiology, University of California Los Angeles

Here, we describe the procedures developed in our laboratory for preparing powders of small molecule crystals for microcrystal electron diffraction (MicroED) experiments.

Tags

Microcrystal Electron Diffraction

-- Views

Related Videos

article

Microcrystallography of Protein Crystals and In Cellulo Diffraction

article

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

article

Semi-automated Biopanning of Bacterial Display Libraries for Peptide Affinity Reagent Discovery and Analysis of Resulting Isolates

article

Capturing the Interaction Kinetics of an Ion Channel Protein with Small Molecules by the Bio-layer Interferometry Assay

article

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

article

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

article

Preparing Lamellae from Vitreous Biological Samples Using a Dual-Beam Scanning Electron Microscope for Cryo-Electron Tomography

article

Micropatterning Transmission Electron Microscopy Grids to Direct Cell Positioning within Whole-Cell Cryo-Electron Tomography Workflows

article

On-Chip Crystallization and Large-Scale Serial Diffraction at Room Temperature

article

The Extraction of Liver Glycogen Molecules for Glycogen Structure Determination

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved