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Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

DOI :

10.3791/62925-v

10:33 min

December 17th, 2021

December 17th, 2021

2,108 Views

1Department of Ophthalmology, University of Washington, 2Academic Unit of Ophthalmology, Translational Health Sciences, University of Bristol

This protocol outlines the steps for inducing Primed Mycobacterial Uveitis (PMU) in mice. This method outlines the steps to help produce reliable and robust ocular inflammation in the mouse model system. Using this protocol, we generated uveitic eyes and uninflamed fellow eyes from single animals for further evaluation with immunologic, transcriptomic, and proteomic assays.

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Primed Mycobacterial Uveitis

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