JoVE Logo
Faculty Resource Center

Sign In

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

DOI :

10.3791/62925-v

10:33 min

December 17th, 2021

December 17th, 2021

2,173 Views

1Department of Ophthalmology, University of Washington, 2Academic Unit of Ophthalmology, Translational Health Sciences, University of Bristol

This protocol outlines the steps for inducing Primed Mycobacterial Uveitis (PMU) in mice. This method outlines the steps to help produce reliable and robust ocular inflammation in the mouse model system. Using this protocol, we generated uveitic eyes and uninflamed fellow eyes from single animals for further evaluation with immunologic, transcriptomic, and proteomic assays.

Tags

Primed Mycobacterial Uveitis

-- Views

Related Videos

article

Introducing Shear Stress in the Study of Bacterial Adhesion

article

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria

article

Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection

article

Study of Phagolysosome Biogenesis in Live Macrophages

article

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells

article

Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite

article

Experimental Infection with Listeria monocytogenes as a Model for Studying Host Interferon-γ Responses

article

Methodologies for Studying B. subtilis Biofilms as a Model for Characterizing Small Molecule Biofilm Inhibitors

article

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

article

Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved