Induction of Skin Pressure Ulcer after Complete SCI
4:22
Post-operative Animal Care, Euthanasia, and Tissue Collection for Histology
5:07
Results: Skin Wound Histology and Impact on Healing
6:15
Conclusion
Transcription
The overall goal of this study is to examine the effect of spinal cord injury on the dynamics of pressure ulcer development and healing in an animal model. The main advantage of this technique is that it does not impair animal movements, and is ve
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Here, we describe a simple method to induce clinically relevant skin pressure ulcers (PUs) in a mouse model of spinal cord injury (SCI). This model can be used in pre-clinical studies to screen for different therapeutics for healing PUs in SCI patients.