Results: Polysome Profiling Analysis of the Developing Mouse Cortex
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Conclusion
Transcript
Translational regulation plays an important role in brain development. Polysome profiling provides a useful and powerful tool to assess the translational status of mRNA, making it possible to examine translational control functions during brain de
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The development of the mammalian brain requires proper control of gene expression at the level of translation. Here, we describe a polysome profiling system with an easy-to-assemble sucrose gradient-making and fractionation platform to assess the translational status of mRNAs in the developing brain.