Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma
6.2K Views
•
07:59 min
•
September 3rd, 2021
DOI :
September 3rd, 2021
•Hiroki Kobayashi1,2,3,4, Krystyna A. Gieniec1,2, Jia Q. Ng1,2, Jarrad Goyne1,2, Tamsin R. M. Lannagan1,2, Elaine M. Thomas1,2, Georgette Radford1,2, Tongtong Wang1,2, Nobumi Suzuki1,2,5, Mari Ichinose1,2, Josephine A. Wright2, Laura Vrbanac1,2, Alastair D. Burt6, Masahide Takahashi3,4,7, Atsushi Enomoto3, Daniel L. Worthley2, Susan L. Woods1,2
1Adelaide Medical School, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Department of Pathology, Nagoya University Graduate School of Medicine, 4Division of Molecular Pathology, Center for Neurological Disease and Cancer, Nagoya University Graduate School of Medicine, 5Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 6Translational and Clinical Research Institute, Newcastle University, 7International Center for Cell and Gene Therapy, Fujita Health University
Chapters in this video
0:04
Introduction
1:18
Portal Vein Injection of Colorectal Cancer Organoids
5:39
Results: Liver Metastases, Tumor Growth Kinetics, Bone Morphogenetic Protein Signaling and Tumor Proliferation Induced by Portal Vein AAV8-Injection
7:29
Conclusion
Related Videos
07:00
Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
16.2K Views
11:43
Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
12.5K Views
07:35
A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer
40.4K Views
07:43
Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis
26.3K Views
09:16
High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor
9.9K Views
00:05
Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury
11.5K Views
08:15
A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
689 Views
03:41
CRC Organoid Culture: A Method to Obtain 3D Organoids from Colorectal Cancer Cells
2.8K Views
05:15
Portal Vein Injection: A Method to Study Cancer Metastasis to the Liver
5.8K Views
04:55
CRC Organoid Cell Labeling: A Method to Generate GFP Lentivirus-transduced Colorectal Cancer Organoid Cells
1.8K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved