Direct Reprogramming of Fibroblasts to Melanocytes
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Results: Direct Reprogramming of Mouse Embryonic Fibroblasts (MEF) into Melanocytes Using Transcription Factors
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Conclusion
Transcrição
Direct reprogramming to generate melanocytes has been reported. However, various transcription factors are used in different studies. In this protocol, we validated and reduced transcription factor number still with higher reprogramming efficiency
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Here, we describe an optimized direct reprogramming system for melanocytes and a high-efficiency, concentrated virus packaging system that ensures smooth direct reprogramming.