JoVE Logo
Faculty Resource Center

Sign In

Culture of Bladder Cancer Organoids as Precision Medicine Tools

DOI :

10.3791/63192-v

December 28th, 2021

December 28th, 2021

3,826 Views

1School of Biomedical Sciences, Faculty of Health, Queensland University of Technology (QUT) at Translational Research Institute, 2Queensland Bladder Cancer Initiative (QBCI), 3Centre for Personalised Analysis of Cancers (CPAC), 4Australian Prostate Cancer Research Centre - Queensland, 5Department of Urology, Princess Alexandra Hospital

Patient-derived organoids (PDOs) are a powerful tool in translational cancer research, reflecting both the genetic and phenotypic heterogeneity of the disease and response to personalized anti-cancer therapies. Here, a consolidated protocol to generate human primary bladder cancer PDOs in preparation for the evaluation of phenotypic analyses and drug responses is detailed.

Tags

Bladder Cancer

-- Views

Related Videos

article

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

article

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

article

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

article

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses

article

Culture, Manipulation, and Orthotopic Transplantation of Mouse Bladder Tumor Organoids

article

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer

article

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

article

Establishment and Culture of Patient-Derived Breast Organoids

article

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

article

Development and Optimization of A Human Hepatocellular Carcinoma Patient-Derived Organoid Model for Potential Target Identification and Drug Discovery

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved