Results: Representative Human Skeletal Muscle Xenograft Analyses
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Conclusion
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This protocol is significant because it can be used to create human skeletal muscle xenografts, which can be used to model muscle disease and to carry out preclinical therapeutic testing. This xenograft model allows researchers to study human musc
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Complex human diseases can be challenging to model in traditional laboratory model systems. Here, we describe a surgical approach to model human muscle disease through the transplantation of human skeletal muscle biopsies into immunodeficient mice.